Selected Publications

All publications can be found on Google Scholar 


Fulneček J, Říha K. High-Throughput Protein-Nucleic Acid Interaction Assay Based on Protein-Induced Fluorescence Enhancement. Methods Mol Biol. 2021;2209:109-117. doi: 10.1007/978-1-0716-0935-4_7.PMID: 33201465


Valuchova S, Mikulkova P, Pecinkova J, Klimova J, Krumnikl M, Bainar P, Heckmann S, Tomancak P, Riha K. Imaging plant germline differentiation within Arabidopsis flowers by light sheet microscopy. Elife. 2020 Feb 11;9. pii: e52546. doi: 10.7554/eLife.52546. PMID: 32041682

Vivek K. Raxwal, Craig G. Simpson, Jiradet Gloggnitzer, Juan Carlos Entinze, Wenbin Guo, Runxuan Zhang, John W.S. Brown,  Karel Riha. Nonsense mediated RNA decay factor UPF1 is critical for post-transcriptional and translational gene regulation in Arabidopsis. bioRxiv

Raxwal VK, Simpson CG, Gloggnitzer J, Entinze JC, Guo W, Zhang R, Brown JWS, Riha K., Nonsense-mediated RNA Decay Factor UPF1 is Critical for Post-transcriptional and Post-translational Gene Regulation in Arabidopsis. Plant Cell. 2020 Jul 14:tpc.00244.2020. doi: 10.1105/tpc.20.00244. Online ahead of print.PMID: 32665305


Javorka P, Raxwal VK, Najvarek J, Riha K. artMAP: A user-friendly tool for mapping ethyl methanesulfonate-induced mutations in Arabidopsis. Plant Direct. 2019 Jun 11;3(6):e00146. doi: 10.1002/pld3.146. eCollection 2019 Jun. PMID: 31245783

Eberhard S, Valuchova S, Ravat J, Fulneček J, Jolivet P, Bujaldon S, Lemaire SD, Wollman FA, Teixeira MT, Riha K, Xu Z.Molecular characterization of Chlamydomonas reinhardtii telomeres and telomerase mutants. Life Sci Alliance. 2019 Jun 3;2(3). pii: e201900315. doi: 10.26508/lsa.201900315. Print 2019 Jun. PMID: 31160377.

Valuchova S, Mikulkova P, Pecinkova J, Klimova J, Krumnikl M, Bainar P, Heckmann S, Tomancak P, Riha K. Imaging plant germline differentiation within Arabidopsis flower by light sheet microscopy. bioRxiv, 774299 


Capitao C, Shukla N, Wandrolova A, Mittelsten Scheid O, Riha K. Functional Characterization of SMG7 Paralogs in Arabidopsis thaliana. Front Plant Sci. 2018 Nov 6;9:1602. doi: 10.3389/fpls.2018.01602. eCollection 2018. PMID: 30459790.

Javorka P, Raxwal VK, Najvarek J, Riha K. artMAP: a user-friendly tool for mapping EMS-induced mutations in Arabidopsis bioRxiv, 414433.


Valuchova S, Fulnecek J, Prokop Z, Stolt-Bergner P, Janouskova E, Hofr C, Riha K. Protection of Arabidopsis Blunt-Ended Telomeres Is Mediated by a Physical Association with the Ku Heterodimer. Plant Cell. 2017 Jun;29(6):1533-1545. doi: 10.1105/tpc.17.00064. Epub 2017 Jun 5. PMID: 28584163.


Valuchova S, Fulnecek J, Petrov AP, Tripsianes K, Riha K. A rapid method for detecting protein-nucleic acid interactions by protein induced fluorescence enhancement. Sci Rep. 2016 Dec 23;6:39653. doi: 10.1038/srep39653. PubMed PMID: 28008962.

Watson JM, Platzer A, Kazda A, Akimcheva S, Valuchova S, Nizhynska V, Nordborg M, Riha K. Germline replications and somatic mutation accumulation are independent of vegetative life span in Arabidopsis. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12226-12231. PubMed PMID: 27729523; PubMed Central PMCID: PMC5087024.

Raxwal VK, Riha K. Nonsense mediated RNA decay and evolutionary capacitance. Biochim Biophys Acta. 2016 Dec;1859(12):1538-1543. doi: 10.1016/j.bbagrm.2016.09.001. Review. PubMed PMID: 27599370.

Valuchova, S., Derboven, E. and Riha, K. Analysis of Telomeric G-overhangs by in-Gel Hybridization. Bio-protocol. 2016 Apr; 6(7): e1775.  

Fulcher N, Riha K. Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana. Front Genet. 2016 Jan 5;6:349. doi: 10.3389/fgene.2015.00349. PubMed PMID: 26779251; PubMed Central PMCID: PMC4700174.

Kazda A, Akimcheva S, Watson JM, Riha K. Cell Proliferation Analysis Using EdU Labeling in Whole Plant and Histological Samples of Arabidopsis. Methods Mol Biol. 2016;1370:169-82. doi: 10.1007/978-1-4939-3142-2_13. PubMed PMID: 26659962.


Fulcher N, Teubenbacher A, Kerdaffrec E, Farlow A, Nordborg M, Riha K. Genetic architecture of natural variation of telomere length in Arabidopsis thaliana. Genetics. 2015 Feb;199(2):625-35. doi: 10.1534/genetics.114.172163. PubMed PMID: 25488978; PubMed Central PMCID: PMC4317667.


Derboven E, Ekker H, Kusenda B, Bulankova P, Riha K. Role of STN1 and DNA polymerase α in telomere stability and genome-wide replication in Arabidopsis. PLoS Genet. 2014 Oct 9;10(10):e1004682. doi: 10.1371/journal.pgen.1004682. PubMed PMID: 25299252; PubMed Central PMCID: PMC4191939.

Gloggnitzer J, Akimcheva S, Srinivasan A, Kusenda B, Riehs N, Stampfl H, Bautor J, Dekrout B, Jonak C, Jiménez-Gómez JM, Parker JE, Riha K. Nonsense-mediated mRNA decay modulates immune receptor levels to regulate plant antibacterial defense. Cell Host Microbe. 2014 Sep 10;16(3):376-90. doi: 10.1016/j.chom.2014.08.010. PubMed PMID: 25211079.

Plecenikova A, Slaninova M, Riha K. Characterization of DNA repair deficient strains of Chlamydomonas reinhardtii generated by insertional mutagenesis. PLoS One. 2014 Aug 21;9(8):e105482. doi: 10.1371/journal.pone.0105482. PubMed PMID: 25144319; PubMed Central PMCID: PMC4140758.

Göhring J, Fulcher N, Jacak J, Riha K. TeloTool: a new tool for telomere length measurement from terminal restriction fragment analysis with improved probe intensity correction. Nucleic Acids Res. 2014 Feb;42(3):e21. doi: 10.1093/nar/gkt1315. PubMed PMID: 24366880; PubMed Central PMCID: PMC3919618.

Fulcher N, Derboven E, Valuchova S, Riha K. If the cap fits, wear it: an overview of telomeric structures over evolution. Cell Mol Life Sci. 2014 Mar;71(5):847-65. doi: 10.1007/s00018-013-1469-z. Review. PubMed PMID: 24042202.


Bulankova P, Akimcheva S, Fellner N, Riha K. Identification of Arabidopsis meiotic cyclins reveals functional diversification among plant cyclin genes. PLoS Genet. 2013 May;9(5):e1003508. doi: 10.1371/journal.pgen.1003508. PubMed PMID: 23671425; PubMed Central PMCID: PMC3649987.


Kazda A, Zellinger B, Rössler M, Derboven E, Kusenda B, Riha K. Chromosome end protection by blunt-ended telomeres. Genes Dev. 2012 Aug 1;26(15):1703-13. doi: 10.1101/gad.194944.112. PubMed PMID: 22810623; PubMed Central PMCID: PMC3418588.

Riehs-Kearnan N, Gloggnitzer J, Dekrout B, Jonak C, Riha K. Aberrant growth and lethality of Arabidopsis deficient in nonsense-mediated RNA decay factors is caused by autoimmune-like response. Nucleic Acids Res. 2012 Jul;40(12):5615-24. doi: 10.1093/nar/gks195. PubMed PMID: 22379136; PubMed Central PMCID: PMC3384318.


Watson JM, Riha K. Telomeres, aging, and plants: from weeds to Methuselah - a mini-review. Gerontology. 2011;57(2):129-36. doi: 10.1159/000310174. Review. PubMed PMID: 20375491.


Bulankova P, Riehs-Kearnan N, Nowack MK, Schnittger A, Riha K. Meiotic progression in Arabidopsis is governed by complex regulatory interactions between SMG7, TDM1, and the meiosis I-specific cyclin TAM. Plant Cell. 2010 Nov;22(11):3791-803. doi: 10.1105/tpc.110.078378. PubMed PMID: 21119056; PubMed Central PMCID: PMC3015126.

Watson JM, Riha K. Comparative biology of telomeres: where plants stand. FEBS Lett. 2010 Sep 10;584(17):3752-9. doi: 10.1016/j.febslet.2010.06.017. Review. PubMed PMID: 20580356; PubMed Central PMCID: PMC3767043.

Vrbsky J, Akimcheva S, Watson JM, Turner TL, Daxinger L, Vyskot B, Aufsatz W, Riha K. siRNA-mediated methylation of Arabidopsis telomeres. PLoS Genet. 2010 Jun 10;6(6):e1000986. doi: 10.1371/journal.pgen.1000986. PubMed PMID: 20548962; PubMed Central PMCID: PMC2883606.


Akimcheva S, Zellinger B, Riha K. Genome stability in Arabidopsis cells exhibiting alternative lengthening of telomeres. Cytogenet Genome Res. 2008;122(3-4):388-95. doi: 10.1159/000167827. PubMed PMID: 19188710.

Riehs N, Akimcheva S, Puizina J, Bulankova P, Idol RA, Siroky J, Schleiffer A, Schweizer D, Shippen DE, Riha K. Arabidopsis SMG7 protein is required for exit from meiosis. J Cell Sci. 2008 Jul 1;121(Pt 13):2208-16. doi: 10.1242/jcs.027862. PubMed PMID: 18544632.


Zellinger B, Akimcheva S, Puizina J, Schirato M, Riha K. Ku suppresses formation of telomeric circles and alternative telomere lengthening in Arabidopsis. Mol Cell. 2007 Jul 6;27(1):163-9. PubMed PMID: 17612498.

Zellinger B, Riha K. Composition of plant telomeres. Biochim Biophys Acta. 2007 May-Jun;1769(5-6):399-409. Review. PubMed PMID: 17383025.


Riha K, Heacock ML, Shippen DE. The role of the nonhomologous end-joining DNA double-strand break repair pathway in telomere biology. Annu Rev Genet. 2006;40:237-77. Review. PubMed PMID: 16822175.


Watson JM, Bulankova P, Riha K, Shippen DE, Vyskot B. Telomerase-independent cell survival in Arabidopsis thaliana. Plant J. 2005 Sep;43(5):662-74. PubMed PMID: 16115064.


Puizina J, Siroky J, Mokros P, Schweizer D, Riha K. Mre11 deficiency in Arabidopsis is associated with chromosomal instability in somatic cells and Spo11-dependent genome fragmentation during meiosis. Plant Cell. 2004 Aug;16(8):1968-78. PubMed PMID: 15258261; PubMed Central PMCID: PMC519189.


Riha K, Shippen DE. Telomere structure, function and maintenance in Arabidopsis. Chromosome Res. 2003;11(3):263-75. Review. PubMed PMID: 12769293.

Riha K, Shippen DE. Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):611-5. PubMed PMID: 12511598; PubMed Central PMCID: PMC141044.


Riha K, Watson JM, Parkey J, Shippen DE. Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. EMBO J. 2002 Jun 3;21(11):2819-26. PubMed PMID: 12032094; PubMed Central PMCID: PMC126030.


Riha K, McKnight TD, Griffing LR, Shippen DE. Living with genome instability: plant responses to telomere dysfunction. Science. 2001 Mar 2;291(5509):1797-800. PubMed PMID: 11230697.


Riha K, McKnight TD, Fajkus J, Vyskot B, Shippen DE. Analysis of the G-overhang structures on plant telomeres: evidence for two distinct telomere architectures. Plant J. 2000 Sep;23(5):633-41. PubMed PMID: 10972889.


Riha K, Fajkus J, Siroky J, Vyskot B. Developmental control of telomere lengths and telomerase activity in plants. Plant Cell. 1998 Oct;10(10):1691-8. PubMed PMID: 9761795; PubMed Central PMCID: PMC143947.